Clinical and Cognitive Neuroscience Lab
The CCNL lab focuses on the neural correlates of cognitive control, with an emphasis on how a controlling brain region (e.g., prefrontal cortex) influences controlled (e.g. sensory-motor) brain regions. A primary objective is understanding failures of cognitive control, particularly in relation to schizophrenia and other psychotic disorders, as well as other conditions that may show differences in cognitive control (including ADHD, Aniridia and obesity). CCNL also investigate the extent to which cognitive control failures may be remediated and the brain circuitry plasticity underlying these time-related changes. The work conducted in the laboratory integrates behavioral and multi-modal functional brain imaging methods (f/MRI, DTI, EEG, and MEG) to provide a comprehensive understanding of these issues. More information »
PI: Brett Clementz & Jennifer E. McDowell
Contact: Brett Clementz
- D.A. Brown, N.A. Lazar, G.S. Datta, W. Jang & J.E. McDowell (in press). Incorporating spatial dependence into Bayesian multiple testing of statistical parametric maps in functional neuroimaging. NeuroImage.
- C.E. Krafft, J.E. Pierce, N.F. Schwarz, L. Chi, A.L. Weinberger, D.J. Schaeffer, A.L. Rodrigue, J. Camchong, J.D. Allison, N.E Yanasak, T. Liu, C.L. Davis & J.E. McDowell (in press). An eight month exercise intervention alters resting state synchrony in overweight children. Neuroscience.
- C.E. Krafft, N.F. Schwarz, L. Chi, A.L. Weinberger, D.J. Schaeffer, J.E. Pierce, A.L. Rodrigue, N.E. Yanasak, P.H. Miller, P.D. Tomporowski, C.L., Davis & J.E. McDowell (in press). An eight month randomized controlled exercise trial alters brain activation during cognitive tasks in overweight children. Obesity.
- J. Lee, C. Park, K.A. Dyckman, N.A. Lazar, B.P. Austin, Q. Li & J.E. McDowell (in press). Practice-related changes in neural activation patterns investigated via wavelet-based clustering analysis. Human Brain Mapping.
- D.J. Schaeffer, M.T. Amlung, Q. Li, C.E. Krafft, B.P Austin, K.A. Dyckman & J.E. McDowell (2013). Neural correlates of behavioral variation in healthy adults’ antisaccade performance. Psychophysiology, 50:325-33.
- J. Camchong, K.A. Dyckman, B.P. Austin, B.A. Clementz & J.E. McDowell (2008). Common neural circuitry supporting volitional saccades and its disruption in schizophrenia patients and relatives. Biological Psychiatry, 64: 1042-1050.
- J.E. McDowell, K.A. Dyckman, B.P. Austin & B.A. Clementz (2008). Neurophysiology and neuroanatomy of reflexive and volitional saccades: Evidence from studies of humans. Brain and Cognition, 38: 255-270.
- K.A. Dyckman, J. Camchong, B.A. Clementz & J.E. McDowell (2007). An effect of context on saccade-related behavior and brain activity. NeuroImage, 36, 774-784.
- J.A. Sweeney, B. Luna, S.K. Keedy, J.E. McDowell & B.A. Clementz (2007). FMRI studies of eye movement control: Investigating the interaction of cognitive and sensorimotor brain systems. NeuroImage, 36, S2 T54-60.